diff --git a/comfy_cli/cmdline.py b/comfy_cli/cmdline.py
index 247ba95a..b7421005 100644
--- a/comfy_cli/cmdline.py
+++ b/comfy_cli/cmdline.py
@@ -375,6 +375,7 @@ def update(
         raise typer.Exit(code=1)
 
     comfy_path = workspace_manager.workspace_path
+    python_exe = workspace_manager.python_exe
 
     if "all" == target:
         custom_nodes.command.execute_cm_cli(["update", "all"])
@@ -386,7 +387,7 @@ def update(
         os.chdir(comfy_path)
         subprocess.run(["git", "pull"], check=True)
         subprocess.run(
-            [sys.executable, "-m", "pip", "install", "-r", "requirements.txt"],
+            [python_exe, "-m", "pip", "install", "-r", "requirements.txt"],
             check=True,
         )
 
diff --git a/comfy_cli/command/custom_nodes/cm_cli_util.py b/comfy_cli/command/custom_nodes/cm_cli_util.py
index d74a1078..6667cf29 100644
--- a/comfy_cli/command/custom_nodes/cm_cli_util.py
+++ b/comfy_cli/command/custom_nodes/cm_cli_util.py
@@ -25,6 +25,7 @@ def execute_cm_cli(args, channel=None, fast_deps=False, mode=None) -> str | None
     _config_manager = ConfigManager()
 
     workspace_path = workspace_manager.workspace_path
+    python_exe = workspace_manager.python_exe
 
     if not workspace_path:
         print("\n[bold red]ComfyUI path is not resolved.[/bold red]\n", file=sys.stderr)
@@ -38,7 +39,7 @@ def execute_cm_cli(args, channel=None, fast_deps=False, mode=None) -> str | None
         )
         raise typer.Exit(code=1)
 
-    cmd = [sys.executable, cm_cli_path] + args
+    cmd = [python_exe, cm_cli_path] + args
 
     if channel is not None:
         cmd += ["--channel", channel]
diff --git a/comfy_cli/command/custom_nodes/command.py b/comfy_cli/command/custom_nodes/command.py
index d826c6c3..cac1aabe 100644
--- a/comfy_cli/command/custom_nodes/command.py
+++ b/comfy_cli/command/custom_nodes/command.py
@@ -70,10 +70,11 @@ def run_script(cmd, cwd="."):
 
 def get_installed_packages():
     global pip_map
+    python_exe = workspace_manager.python_exe
 
     if pip_map is None:
         try:
-            result = subprocess.check_output([sys.executable, "-m", "pip", "list"], universal_newlines=True)
+            result = subprocess.check_output([python_exe, "-m", "pip", "list"], universal_newlines=True)
 
             pip_map = {}
             for line in result.split("\n"):
@@ -138,6 +139,7 @@ def try_install_script(repo_path, install_cmd, instant_execution=False):
 
 
 def execute_install_script(repo_path):
+    python_exe = workspace_manager.python_exe
     install_script_path = os.path.join(repo_path, "install.py")
     requirements_path = os.path.join(repo_path, "requirements.txt")
 
@@ -157,13 +159,13 @@ def execute_install_script(repo_path):
                 # package_name = remap_pip_package(line.strip())
                 package_name = line.strip()
                 if package_name and not package_name.startswith("#"):
-                    install_cmd = [sys.executable, "-m", "pip", "install", package_name]
+                    install_cmd = [python_exe, "-m", "pip", "install", package_name]
                     if package_name.strip() != "":
                         try_install_script(repo_path, install_cmd)
 
     if os.path.exists(install_script_path):
         print("Install: install script")
-        install_cmd = [sys.executable, "install.py"]
+        install_cmd = [python_exe, "install.py"]
         try_install_script(repo_path, install_cmd)
 
 
@@ -481,6 +483,7 @@ def uninstall(
 def update_node_id_cache():
     config_manager = ConfigManager()
     workspace_path = workspace_manager.workspace_path
+    python_exe = workspace_manager.python_exe
 
     cm_cli_path = os.path.join(workspace_path, "custom_nodes", "ComfyUI-Manager", "cm-cli.py")
 
@@ -489,7 +492,7 @@ def update_node_id_cache():
         os.makedirs(tmp_path)
 
     cache_path = os.path.join(tmp_path, "node-cache.list")
-    cmd = [sys.executable, cm_cli_path, "export-custom-node-ids", cache_path]
+    cmd = [python_exe, cm_cli_path, "export-custom-node-ids", cache_path]
 
     new_env = os.environ.copy()
     new_env["COMFYUI_PATH"] = workspace_path
diff --git a/comfy_cli/command/install.py b/comfy_cli/command/install.py
index abb26229..f0179561 100755
--- a/comfy_cli/command/install.py
+++ b/comfy_cli/command/install.py
@@ -37,6 +37,7 @@ def pip_install_comfyui_dependencies(
     skip_requirement: bool,
 ):
     os.chdir(repo_dir)
+    python_exe = workspace_manager.python_exe
 
     result = None
     if not skip_torch_or_directml:
@@ -45,7 +46,7 @@ def pip_install_comfyui_dependencies(
             pip_url = ["--extra-index-url", "https://download.pytorch.org/whl/rocm6.0"]
             result = subprocess.run(
                 [
-                    sys.executable,
+                    python_exe,
                     "-m",
                     "pip",
                     "install",
@@ -60,7 +61,7 @@ def pip_install_comfyui_dependencies(
         # install torch for NVIDIA
         if gpu == GPU_OPTION.NVIDIA:
             base_command = [
-                sys.executable,
+                python_exe,
                 "-m",
                 "pip",
                 "install",
@@ -102,12 +103,12 @@ def pip_install_comfyui_dependencies(
             utils.install_conda_package("libuv")
             # TODO: wrap pip install in a function
             subprocess.run(
-                [sys.executable, "-m", "pip", "install", "mkl", "mkl-dpcpp"],
+                [python_exe, "-m", "pip", "install", "mkl", "mkl-dpcpp"],
                 check=True,
             )
             result = subprocess.run(
                 [
-                    sys.executable,
+                    python_exe,
                     "-m",
                     "pip",
                     "install",
@@ -125,13 +126,13 @@ def pip_install_comfyui_dependencies(
 
         # install directml for AMD windows
         if gpu == GPU_OPTION.AMD and plat == constants.OS.WINDOWS:
-            result = subprocess.run([sys.executable, "-m", "pip", "install", "torch-directml"], check=True)
+            result = subprocess.run([python_exe, "-m", "pip", "install", "torch-directml"], check=True)
 
         # install torch for Mac M Series
         if gpu == GPU_OPTION.MAC_M_SERIES:
             result = subprocess.run(
                 [
-                    sys.executable,
+                    python_exe,
                     "-m",
                     "pip",
                     "install",
@@ -148,7 +149,7 @@ def pip_install_comfyui_dependencies(
     # install requirements.txt
     if skip_requirement:
         return
-    result = subprocess.run([sys.executable, "-m", "pip", "install", "-r", "requirements.txt"], check=False)
+    result = subprocess.run([python_exe, "-m", "pip", "install", "-r", "requirements.txt"], check=False)
     if result.returncode != 0:
         rprint("Failed to install ComfyUI dependencies. Please check your environment (`comfy env`) and try again.")
         sys.exit(1)
@@ -156,8 +157,10 @@ def pip_install_comfyui_dependencies(
 
 # install requirements for manager
 def pip_install_manager_dependencies(repo_dir):
+    python_exe =  workspace_manager.python_exe
+
     os.chdir(os.path.join(repo_dir, "custom_nodes", "ComfyUI-Manager"))
-    subprocess.run([sys.executable, "-m", "pip", "install", "-r", "requirements.txt"], check=True)
+    subprocess.run([python_exe, "-m", "pip", "install", "-r", "requirements.txt"], check=True)
 
 
 def execute(
diff --git a/comfy_cli/command/launch.py b/comfy_cli/command/launch.py
index 52885e66..1c940019 100644
--- a/comfy_cli/command/launch.py
+++ b/comfy_cli/command/launch.py
@@ -34,6 +34,8 @@ def launch_comfyui(extra):
     # To minimize the possibility of leaving residue in the tmp directory, use files instead of directories.
     reboot_path = os.path.join(session_path + ".reboot")
 
+    python_exe = workspace_manager.python_exe
+
     extra = extra if extra is not None else []
 
     process = None
@@ -41,7 +43,7 @@ def launch_comfyui(extra):
     if "COMFY_CLI_BACKGROUND" not in os.environ:
         # If not running in background mode, there's no need to use popen. This can prevent the issue of linefeeds occurring with tqdm.
         while True:
-            res = subprocess.run([sys.executable, "main.py"] + extra, env=new_env, check=False)
+            res = subprocess.run([python_exe, "main.py"] + extra, env=new_env, check=False)
 
             if reboot_path is None:
                 print("[bold red]ComfyUI is not installed.[/bold red]\n")
@@ -70,7 +72,7 @@ def redirector_stdout():
             while True:
                 if sys.platform == "win32":
                     process = subprocess.Popen(
-                        [sys.executable, "main.py"] + extra,
+                        [python_exe, "main.py"] + extra,
                         stdout=subprocess.PIPE,
                         stderr=subprocess.PIPE,
                         text=True,
@@ -81,7 +83,7 @@ def redirector_stdout():
                     )
                 else:
                     process = subprocess.Popen(
-                        [sys.executable, "main.py"] + extra,
+                        [python_exe, "main.py"] + extra,
                         text=True,
                         env=new_env,
                         encoding="utf-8",
diff --git a/comfy_cli/workspace_manager.py b/comfy_cli/workspace_manager.py
index fc5f451a..764915a6 100644
--- a/comfy_cli/workspace_manager.py
+++ b/comfy_cli/workspace_manager.py
@@ -1,5 +1,7 @@
 import concurrent.futures
 import os
+import sys
+import subprocess
 from dataclasses import dataclass, field
 from datetime import datetime
 from enum import Enum
@@ -151,6 +153,7 @@ def __init__(
         self.use_recent = None
         self.workspace_path = None
         self.workspace_type = None
+        self.python_exe = None
         self.skip_prompting = None
 
     def setup_workspace_manager(
@@ -164,6 +167,7 @@ def setup_workspace_manager(
         self.use_here = use_here
         self.use_recent = use_recent
         self.workspace_path, self.workspace_type = self.get_workspace_path()
+        self.python_exe = self.find_or_create_python_env()
         self.skip_prompting = skip_prompting
 
     def set_recent_workspace(self, path: str):
@@ -316,3 +320,50 @@ def fill_print_table(self, table):
             "Current selected workspace",
             f"[bold green]→ {self.workspace_path}[/bold green]",
         )
+    
+    def find_or_create_python_env(self, default_name=".venv"):
+        """
+        Locates the Conda/virtual environment to use, else creates `.venv`.
+        """
+        # Case 1: Find if .venv or venv is present in install directory.
+        for name in [default_name, "venv"]:
+            if utils.get_os() == constants.OS.WINDOWS:
+                venv_path = os.path.join(self.workspace_path, name, "Scripts", "python.exe")
+            else:
+                venv_path = os.path.join(self.workspace_path, name, "bin", "python")
+            if os.path.exists(venv_path):
+                return venv_path
+
+        # Case 2: If CONDA_PREFIX is present, use the conda environment.
+        conda_prefix = os.environ.get("CONDA_PREFIX")
+        if conda_prefix:
+            if utils.get_os() == constants.OS.WINDOWS:
+                return os.path.join(conda_prefix, "python.exe")
+            else:
+                return os.path.join(conda_prefix, "bin", "python")
+
+        
+        # Case 3: Create standalone venv using currently active Python executable.
+        try:
+            print("[bold yellow]Virtual environment not found. Creating...[/bold yellow]")
+            # TODO: Should probably check here if Python version is compatible.
+            subprocess.check_call(
+                [
+                    sys.executable,
+                    "-m",
+                    "venv",
+                    "--copies",
+                    "--upgrade-deps",
+                    "--prompt",
+                    "comfyui",
+                    os.path.join(self.workspace_path, default_name),
+                ]
+            )
+            if utils.get_os() == constants.OS.WINDOWS:
+                return os.path.join(self.workspace_path, default_name, "Scripts", "python.exe")
+            else:
+                return os.path.join(self.workspace_path, default_name, "bin", "python")
+        except subprocess.CalledProcessError as e:
+            print(f"[bold red]Failed to create virtual environment: {e}[/bold red]")
+            raise typer.Exit(code=1)
+