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add operationalization details for PathOS case studies across multiple indicators
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sections/1_open_science/availability_data_repositories.qmd

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##### Core Trust Seal
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Core Trust Seal is a non-profit organisation that labels data sources with their seal if data sources adhere to the FAIR principles. On the website a [list](https://amt.coretrustseal.org/certificates/) is maintained with all the data sources that the seal has been assigned to. Data stored in these sources can thus be considered to be produced in accordance with the FAIR principles. When performing research related to the availability of data repositories, one can consider repositories that have received the CoreTrustSeal, the Nestor Seal DIN31644, the ISO16363 certification, or similar, to be automatically trusted [@jahn2023].
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Core Trust Seal is a non-profit organisation that labels data sources with their seal if data sources adhere to the FAIR principles. On the website a [list](https://amt.coretrustseal.org/certificates/) is maintained with all the data sources that the seal has been assigned to. Data stored in these sources can thus be considered to be produced in accordance with the FAIR principles. When performing research related to the availability of data repositories, one can consider repositories that have received the CoreTrustSeal, the Nestor Seal DIN31644, the ISO16363 certification, or similar, to be automatically trusted [@jahn2023].
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- Effects of Data Repositories on Data Usage
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

sections/1_open_science/availability_preprint_repositories.qmd

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All repositories in both data sources are Open Access.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- French Open Access Infrastructure
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).
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# Known correlates
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The availability of preprint repositories **may** correlate with specific fields of study, given that certain scientific disciplines are more inclined to use preprints than others. Furthermore, regional or national open science policies, funding opportunities, and research culture can also influence the presence or absence of preprint repositories in a particular country or region.

sections/1_open_science/availability_publication_repositories.qmd

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All repositories in both data sources are Open Access.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- French Open Access Infrastructure
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).
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# Known correlates
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Various factors **may** influence the availability of publication repositories in specific fields, countries, or organizations such as: research output, research funding, technological infrastructure, Open Access mandates, research collaboration, overall research infrastructure.

sections/1_open_science/prevalence_open_access_publishing.qmd

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Once we know the Open Access status of each publication, we can easily calculate the percentage, simply as the number of publications out of the total that are Open Access. Additionally, we can do this for each separate Open Access type. We could for example refer to the % Green OA or % Gold OA. Note that percentages may not add up to 100%, but the total may also even exceed 100%, because publications can have both a Green Open Access status and another Open Access status. For that reason, you should not report percentages of Open Access statuses in a cumulative fashion (e.g. not in a stacked bar chart), in particular not when reporting on Green Open Access.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- French Open Access Infrastructure
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).
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# Known correlates
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There is a large ongoing debate whether Open Access publishing increases the citation impact of publications, known as the so-called Open Access citation advantage. A recent systematic review on the topic suggests that the evidence is inconclusive [@langham-putrow2021].

sections/2_academic_impact/citation_impact.qmd

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The database is closed access, and we therefore do not provide more details about API usage.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- Impact of Artefact Reuse in COVID-19 Publications
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- Impact of Open Access Routes on Topic Persistence
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- Portuguese Repository Infrastructure RCAAP
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- ELIXIR´s Bioinformatics Resources
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).
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# Known correlates
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As already clarified, citations are affected in general by field and publication year, and these are quite clearly causal effects. There are many other factors that correlate with citations [@onodera2015], for which most it is unclear whether the effect is causal. One factor that is consistently associated with more citations is collaboration [@larivière2015], which is potentially driven by network effects [@schulz]. In addition, there is evidence for a clear causal effect of the journal where something is published on citations [@traag2021].

sections/2_academic_impact/extra-academic_collaboration.qmd

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The data sources described in the previous section can be used to populate this double entry table for a given piece of research, a set of researches or (even more interestingly) several sets of researches whose different collaboration-profile can be assessed comparing their value for each of the cell, row or column as well as for the entire table.
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In particular, all the metrics matrix and the data source described above can be employed to assess collaboration in OS but also in non-OS projects, allowing to investigate whether open science is less or more prone to facilitate specific types of collaboration. Similarly, the comparison can be carried out by disciplinary field, type of research, project size or duration, type of funding, etc.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- ELIXIR´s Bioinformatics Resources
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

sections/2_academic_impact/thematic_persistence.qmd

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Continuity is evaluated by the **strength of inter-year linkages** among topic clusters.\
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This allows distinguishing different **modes of persistence** and topic evolution.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- Impact of Open Access Routes on Topic Persistence
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

sections/2_academic_impact/use_of_data_in_research.qmd

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##### Standardization protocols
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To combat the issue of standardization for the tracking of clicks/views/downloads of data use in research [The COUNTER Code of Practice for Research Data](https://www.countermetrics.org/code-of-practice/) gives guidance on how to standardize count systems for data use. The guidelines provided by The COUNTER Code of Practice for Research Data can be followed to make inquiries in data retrieval information more comparable among researchers.
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To combat the issue of standardization for the tracking of clicks/views/downloads of data use in research [The COUNTER Code of Practice for Research Data](https://www.countermetrics.org/code-of-practice/) gives guidance on how to standardize count systems for data use. The guidelines provided by The COUNTER Code of Practice for Research Data can be followed to make inquiries in data retrieval information more comparable among researchers.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- Effects of Data Repositories on Data Usage
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

sections/3_societal_impact/OS_access_advantage.qmd

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As an example, one can (1) focus on the scientific domains associated with the accessed resources and (2) aggregate the IP-related information in countries and industrial sectors, for example follwiong the NACE typology ([ec.europa.eu/eurostat/web/nace](https://ec.europa.eu/eurostat/web/nace)).
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This data structure allows to observe not only the general access advantage (or disadvantage) of different type of scientific ressource, but to break the calculation down to different combination of scientific domains, countries and industrial sectors, in order to facilitate comparison and detect potential confounding factors.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- French Open Access Infrastructure
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

sections/3_societal_impact/scientific_literacy.qmd

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Besides the PISA instrument, there is a great variety of other instruments used to assess scientific literacy, commonly aligned with vision II and the PISA conceptualization. In general, the focus seems to have shifted from viewing scientific literacy as one single ability to defining it as a multidimensional construct. Most of the instruments' contents focus on a specific domain or context (e.g., biology), employing various formats to test skills. The majority of instruments have been developed for use in (secondary school) students and have mainly been employed in that context [@coppi2023; @opitz2017].
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A relatively recent and broadly used instrument is the Test of Scientific Literacy Skills (TOSLS), developed to be a comprehensive and psychometrically sound measure that can be employed on a large scale. The TOSLS includes 28 multiple-choice questions presented through realistic scenarios and requiring respondents to use skills that relate to understanding scientific methods and interpreting data [@gormally2012]. The instrument is available as the supplement to @gormally2012.
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# Operationalization in PathOS Case Studies
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This indicator has been operationalized in the following case studies:
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- French Open Access Infrastructure
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Further details are available in Deliverable D3.3 of PathOS, accessible through the [PathOS Zenodo community](https://zenodo.org/communities/pathos/records?q=&l=list&p=1&s=10&sort=newest).

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