diff --git a/setup.py b/setup.py
index 3f150612..253d1e08 100755
--- a/setup.py
+++ b/setup.py
@@ -217,10 +217,15 @@ def get_compiler_settings(version_str):
                 '/opt/homebrew/include',
                 expanduser('~/homebrew/include'),
             ]
+            _HOMEBREW_PREFIX = os.environ.get('HOMEBREW_PREFIX')
+            if _HOMEBREW_PREFIX is not None:
+                dirs.insert(0, os.path.join(_HOMEBREW_PREFIX, 'include'))
             settings['include_dirs'].extend(dir for dir in dirs if isdir(dir))
             # unixODBC make/install places libodbc.dylib in /usr/local/lib/ by default
             # ( also OS/X since El Capitan prevents /usr/lib from being accessed )
             settings['library_dirs'] = ['/usr/local/lib', '/opt/homebrew/lib']
+            if _HOMEBREW_PREFIX is not None:
+                settings['library_dirs'].insert(1, os.path.join(_HOMEBREW_PREFIX, 'lib'))
     else:
         # Other posix-like: Linux, Solaris, etc.