diff --git a/qiskit_experiments/framework/__init__.py b/qiskit_experiments/framework/__init__.py
index 2f4304ebf2..ce96bb7052 100644
--- a/qiskit_experiments/framework/__init__.py
+++ b/qiskit_experiments/framework/__init__.py
@@ -125,8 +125,9 @@
     BackendData
     BackendTiming
     RestlessMixin
+    SimpleCircuitExtenderMixin
 
-"""
+    """
 from qiskit.providers.options import Options
 from qiskit_experiments.framework.backend_data import BackendData
 from qiskit_experiments.framework.analysis_result import AnalysisResult
@@ -155,3 +156,4 @@
 )
 from .json import ExperimentEncoder, ExperimentDecoder
 from .restless_mixin import RestlessMixin
+from .transpile_mixin import SimpleCircuitExtenderMixin
diff --git a/qiskit_experiments/framework/transpile_mixin.py b/qiskit_experiments/framework/transpile_mixin.py
new file mode 100644
index 0000000000..26d655ca94
--- /dev/null
+++ b/qiskit_experiments/framework/transpile_mixin.py
@@ -0,0 +1,98 @@
+# This code is part of Qiskit.
+#
+# (C) Copyright IBM 2021.
+#
+# This code is licensed under the Apache License, Version 2.0. You may
+# obtain a copy of this license in the LICENSE.txt file in the root directory
+# of this source tree or at http://www.apache.org/licenses/LICENSE-2.0.
+#
+# Any modifications or derivative works of this code must retain this
+# copyright notice, and modified files need to carry a notice indicating
+# that they have been altered from the originals.
+
+"""Transpile mixin class."""
+
+from __future__ import annotations
+from typing import Protocol
+
+from qiskit import QuantumCircuit, QuantumRegister, transpile
+from qiskit.providers import Backend
+
+
+class TranspileMixInProtocol(Protocol):
+    """A protocol to define a class that can be mixed with transpiler mixins."""
+
+    @property
+    def physical_qubits(self):
+        """Return the device qubits for the experiment."""
+
+    @property
+    def backend(self) -> Backend | None:
+        """Return the backend for the experiment"""
+
+    def circuits(self) -> list[QuantumCircuit]:
+        """Return a list of experiment circuits.
+
+        Returns:
+            A list of :class:`~qiskit.circuit.QuantumCircuit`.
+
+        .. note::
+            These circuits should be on qubits ``[0, .., N-1]`` for an
+            *N*-qubit experiment. The circuits mapped to physical qubits
+            are obtained via the internal :meth:`_transpiled_circuits` method.
+        """
+
+    def _transpiled_circuits(self) -> list[QuantumCircuit]:
+        ...
+
+
+class SimpleCircuitExtenderMixin:
+    """A transpiler mixin class that maps virtual qubit index to physical.
+
+    When the backend is not set, the experiment class naively assumes
+    there are max(physical_qubits) + 1 qubits in the quantum circuits.
+    """
+
+    def _transpiled_circuits(
+        self: TranspileMixInProtocol,
+    ) -> list:
+        if hasattr(self.backend, "target"):
+            # V2 backend model
+            # This model assumes qubit dependent instruction set,
+            # but we assume experiment mixed with this class doesn't have such architecture.
+            basis_gates = set(self.backend.target.operation_names)
+            n_qubits = self.backend.target.num_qubits
+        elif hasattr(self.backend, "configuration"):
+            # V1 backend model
+            basis_gates = set(self.backend.configuration().basis_gates)
+            n_qubits = self.backend.configuration().n_qubits
+        else:
+            # Backend is not set. Naively guess qubit size.
+            basis_gates = None
+            n_qubits = max(self.physical_qubits) + 1
+        return [self._index_mapper(c, basis_gates, n_qubits) for c in self.circuits()]
+
+    def _index_mapper(
+        self: TranspileMixInProtocol,
+        v_circ: QuantumCircuit,
+        basis_gates: set[str] | None,
+        n_qubits: int,
+    ) -> QuantumCircuit:
+        if basis_gates is not None and not basis_gates.issuperset(
+            set(v_circ.count_ops().keys()) - {"barrier"}
+        ):
+            # In Qiskit provider model barrier is not included in target.
+            # Use standard circuit transpile when circuit is not ISA.
+            return transpile(
+                v_circ,
+                backend=self.backend,
+                initial_layout=list(self.physical_qubits),
+            )
+        p_qregs = QuantumRegister(n_qubits)
+        v_p_map = {q: p_qregs[self.physical_qubits[i]] for i, q in enumerate(v_circ.qubits)}
+        p_circ = QuantumCircuit(p_qregs, *v_circ.cregs)
+        p_circ.metadata = v_circ.metadata
+        for inst, v_qubits, clbits in v_circ.data:
+            p_qubits = list(map(v_p_map.get, v_qubits))
+            p_circ._append(inst, p_qubits, clbits)
+        return p_circ
diff --git a/qiskit_experiments/library/characterization/t1.py b/qiskit_experiments/library/characterization/t1.py
index 6f3c02cfc1..7f3c7b5577 100644
--- a/qiskit_experiments/library/characterization/t1.py
+++ b/qiskit_experiments/library/characterization/t1.py
@@ -19,11 +19,16 @@
 from qiskit.circuit import QuantumCircuit
 from qiskit.providers.backend import Backend
 
-from qiskit_experiments.framework import BackendTiming, BaseExperiment, Options
+from qiskit_experiments.framework import (
+    SimpleCircuitExtenderMixin,
+    BackendTiming,
+    BaseExperiment,
+    Options,
+)
 from qiskit_experiments.library.characterization.analysis.t1_analysis import T1Analysis
 
 
-class T1(BaseExperiment):
+class T1(SimpleCircuitExtenderMixin, BaseExperiment):
     r"""An experiment to measure the qubit relaxation time.
 
     # section: overview
diff --git a/qiskit_experiments/library/characterization/t2ramsey.py b/qiskit_experiments/library/characterization/t2ramsey.py
index b4b06be794..79a80975e6 100644
--- a/qiskit_experiments/library/characterization/t2ramsey.py
+++ b/qiskit_experiments/library/characterization/t2ramsey.py
@@ -21,11 +21,16 @@
 from qiskit import QuantumCircuit
 from qiskit.providers.backend import Backend
 
-from qiskit_experiments.framework import BackendTiming, BaseExperiment, Options
+from qiskit_experiments.framework import (
+    SimpleCircuitExtenderMixin,
+    BackendTiming,
+    BaseExperiment,
+    Options,
+)
 from qiskit_experiments.library.characterization.analysis.t2ramsey_analysis import T2RamseyAnalysis
 
 
-class T2Ramsey(BaseExperiment):
+class T2Ramsey(SimpleCircuitExtenderMixin, BaseExperiment):
     r"""An experiment to measure the Ramsey frequency and the qubit dephasing time
     sensitive to inhomogeneous broadening.
 
diff --git a/releasenotes/notes/add-transpiler-mixin-9b30296518e5f4ba.yaml b/releasenotes/notes/add-transpiler-mixin-9b30296518e5f4ba.yaml
new file mode 100644
index 0000000000..f956c76d6a
--- /dev/null
+++ b/releasenotes/notes/add-transpiler-mixin-9b30296518e5f4ba.yaml
@@ -0,0 +1,21 @@
+---
+developer:
+  - |
+    Add a mixin class :class:`~.SimpleCircuitExtenderMixin` that automatically
+    implements the :meth:`.BaseExperiment._transpiled_circuits` method for 
+    simple experiments that require neither gate translation nor routing,
+    i.e. experiment that directly creates ISA circuits.
+    This bypasses the call to the Qiskit transpiler, which makes your experiment run more performant.
+    For example:
+
+    .. code-block::python
+
+      from qiskit_experiment.framework import BaseExperiment, SimpleCircuitExtenderMixin
+
+      class MyExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+
+        def circuits(self):
+          qc = QuantumCircuit(1, 1)
+          qc.x(0)
+          qc.measure(0, 0)
+          return [qc]
diff --git a/test/framework/test_transpile_mixin.py b/test/framework/test_transpile_mixin.py
new file mode 100644
index 0000000000..17ec198101
--- /dev/null
+++ b/test/framework/test_transpile_mixin.py
@@ -0,0 +1,164 @@
+# This code is part of Qiskit.
+#
+# (C) Copyright IBM 2021.
+#
+# This code is licensed under the Apache License, Version 2.0. You may
+# obtain a copy of this license in the LICENSE.txt file in the root directory
+# of this source tree or at http://www.apache.org/licenses/LICENSE-2.0.
+#
+# Any modifications or derivative works of this code must retain this
+# copyright notice, and modified files need to carry a notice indicating
+# that they have been altered from the originals.
+
+"""Tests for transpile mixin."""
+
+from test.base import QiskitExperimentsTestCase
+from test.fake_experiment import FakeAnalysis
+
+from qiskit import QuantumCircuit
+from qiskit.providers.fake_provider import GenericBackendV2
+
+from qiskit_experiments.framework import SimpleCircuitExtenderMixin, BaseExperiment
+from qiskit_experiments.framework.composite import ParallelExperiment
+
+
+class TestSimpleCircuitExtender(QiskitExperimentsTestCase):
+    """A test for SimpleCircuitExtender MixIn."""
+
+    def test_transpiled_single_qubit_circuits(self):
+        """Test fast-transpile with single qubit circuit."""
+
+        class _MockExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+            def circuits(self) -> list:
+                qc1 = QuantumCircuit(1, 1)
+                qc1.x(0)
+                qc1.measure(0, 0)
+                qc1.metadata = {"test_val": "123"}
+
+                qc2 = QuantumCircuit(1, 1)
+                qc2.sx(0)
+                qc2.measure(0, 0)
+                qc2.metadata = {"test_val": "456"}
+                return [qc1, qc2]
+
+        num_qubits = 10
+
+        mock_backend = GenericBackendV2(num_qubits, basis_gates=["x", "sx", "measure"])
+        exp = _MockExperiment((3,), backend=mock_backend)
+        test_circs = exp._transpiled_circuits()
+
+        self.assertEqual(len(test_circs), 2)
+        c0, c1 = test_circs
+
+        # output size
+        self.assertEqual(len(c0.qubits), num_qubits)
+        self.assertEqual(len(c1.qubits), num_qubits)
+
+        # metadata
+        self.assertDictEqual(c0.metadata, {"test_val": "123"})
+
+        # qubit index of X gate
+        self.assertEqual(c0.qubits.index(c0.data[0][1][0]), 3)
+
+        # creg index of measure
+        self.assertEqual(c0.clbits.index(c0.data[1][2][0]), 0)
+
+        # metadata
+        self.assertDictEqual(c1.metadata, {"test_val": "456"})
+
+        # qubit index of SX gate
+        self.assertEqual(c1.qubits.index(c1.data[0][1][0]), 3)
+
+        # creg index of measure
+        self.assertEqual(c1.clbits.index(c1.data[1][2][0]), 0)
+
+    def test_transpiled_two_qubit_circuits(self):
+        """Test fast-transpile with two qubit circuit."""
+
+        class _MockExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+            def circuits(self) -> list:
+                qc = QuantumCircuit(2, 2)
+                qc.cx(0, 1)
+                qc.measure(0, 0)
+                qc.measure(1, 1)
+                return [qc]
+
+        num_qubits = 10
+
+        mock_backend = GenericBackendV2(num_qubits, basis_gates=["cx", "measure"])
+        exp = _MockExperiment((9, 2), backend=mock_backend)
+        test_circ = exp._transpiled_circuits()[0]
+
+        self.assertEqual(len(test_circ.qubits), num_qubits)
+
+        # qubit index of CX control qubit
+        self.assertEqual(test_circ.qubits.index(test_circ.data[0][1][0]), 9)
+
+        # qubit index of CX target qubit
+        self.assertEqual(test_circ.qubits.index(test_circ.data[0][1][1]), 2)
+
+        # creg index of measure
+        self.assertEqual(test_circ.clbits.index(test_circ.data[1][2][0]), 0)
+        self.assertEqual(test_circ.clbits.index(test_circ.data[2][2][0]), 1)
+
+    def test_empty_backend(self):
+        """Test fast-transpile without backend."""
+
+        class _MockExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+            def circuits(self) -> list:
+                qc = QuantumCircuit(1, 1)
+                qc.x(0)
+                qc.measure(0, 0)
+
+                return [qc]
+
+        exp = _MockExperiment((10,))
+        test_circ = exp._transpiled_circuits()[0]
+
+        self.assertEqual(len(test_circ.qubits), 11)
+
+        # qubit index of X gate
+        self.assertEqual(test_circ.qubits.index(test_circ.data[0][1][0]), 10)
+
+    def test_empty_backend_with_parallel(self):
+        """Test fast-transpile without backend. Circuit qubit location must not overlap."""
+
+        class _MockExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+            def __init__(self, physical_qubits):
+                super().__init__(physical_qubits, FakeAnalysis())
+
+            def circuits(self) -> list:
+                qc = QuantumCircuit(1, 1)
+                qc.x(0)
+                qc.measure(0, 0)
+
+                return [qc]
+
+        exp1 = _MockExperiment((3,))
+        exp2 = _MockExperiment((15,))
+        pexp = ParallelExperiment([exp1, exp2], flatten_results=True)
+        test_circ = pexp._transpiled_circuits()[0]
+
+        self.assertEqual(len(test_circ.qubits), 16)
+
+        # qubit index of X gate
+        self.assertEqual(test_circ.qubits.index(test_circ.data[0][1][0]), 3)
+        self.assertEqual(test_circ.qubits.index(test_circ.data[2][1][0]), 15)
+
+    def test_circuit_non_isa(self):
+        """Test fast-transpile with non-ISA circuit. It should use standard transpile."""
+
+        class _MockExperiment(SimpleCircuitExtenderMixin, BaseExperiment):
+            def circuits(self) -> list:
+                qc = QuantumCircuit(1, 1)
+                qc.x(0)
+                qc.measure(0, 0)
+
+                return [qc]
+
+        mock_backend = GenericBackendV2(1, basis_gates=["sx", "rz", "measure"])
+        exp = _MockExperiment((0,), backend=mock_backend)
+        test_circ = exp._transpiled_circuits()[0]
+
+        # gate is translated into sx-sx-measure
+        self.assertEqual(len(test_circ.data), 3)
diff --git a/test/library/characterization/test_t1.py b/test/library/characterization/test_t1.py
index 7f2d46f6ec..5c8d9db1e4 100644
--- a/test/library/characterization/test_t1.py
+++ b/test/library/characterization/test_t1.py
@@ -252,7 +252,7 @@ def test_t1_parallel_exp_transpile(self):
         instruction_durations = []
         for i in range(num_qubits):
             instruction_durations += [
-                ("rx", [i], (i + 1) * 10, "ns"),
+                ("x", [i], (i + 1) * 10, "ns"),
                 ("measure", [i], (i + 1) * 1000, "ns"),
             ]
         coupling_map = [[i - 1, i] for i in range(1, num_qubits)]
@@ -272,14 +272,14 @@ def test_t1_parallel_exp_transpile(self):
         for circ in circs:
             self.assertEqual(circ.num_qubits, 2)
             op_counts = circ.count_ops()
-            self.assertEqual(op_counts.get("rx"), 2)
+            self.assertEqual(op_counts.get("x"), 2)
             self.assertEqual(op_counts.get("delay"), 2)
 
         tcircs = parexp._transpiled_circuits()
         for circ in tcircs:
             self.assertEqual(circ.num_qubits, num_qubits)
             op_counts = circ.count_ops()
-            self.assertEqual(op_counts.get("rx"), 2)
+            self.assertEqual(op_counts.get("x"), 2)
             self.assertEqual(op_counts.get("delay"), 2)
 
     def test_experiment_config(self):