diff --git a/samples/modules/thrift/hello/README.rst b/samples/modules/thrift/hello/README.rst
index a773bc547b56d..53b400a4c0bfa 100644
--- a/samples/modules/thrift/hello/README.rst
+++ b/samples/modules/thrift/hello/README.rst
@@ -57,12 +57,23 @@ Requirements
    west update
 
 - QEMU Networking (described in :ref:`networking_with_qemu`)
-- Thrift dependencies installed for your host OS e.g. in Ubuntu
+- Thrift dependencies installed for your host OS
 
-.. code-block:: console
-   :caption: Install additional dependencies in Ubuntu
+.. tabs::
+
+   .. group-tab:: Ubuntu
+
+      .. code-block:: bash
+        :caption: Install thrift dependencies in Ubuntu
+
+         sudo apt install -y libboost-all-dev thrift-compiler libthrift-dev
+
+   .. group-tab:: macOS
+
+      .. code-block:: bash
+        :caption: Install thrift dependencies in macOS
 
-   sudo apt install -y libboost-all-dev thrift-compiler libthrift-dev
+         brew install boost openssl thrift
 
 Building and Running
 ********************
diff --git a/samples/modules/thrift/hello/client/Makefile b/samples/modules/thrift/hello/client/Makefile
index dabdf64c0ca74..218fd0928e9ed 100644
--- a/samples/modules/thrift/hello/client/Makefile
+++ b/samples/modules/thrift/hello/client/Makefile
@@ -3,6 +3,8 @@
 
 .PHONY: all clean
 
+OS = $(shell uname -s)
+
 CXXFLAGS :=
 CXXFLAGS += -std=c++17
 
@@ -14,6 +16,14 @@ GENOBJ = $(filter-out %.h, $(GENSRC:.cpp=.o))
 THRIFT_FLAGS :=
 THRIFT_FLAGS += $(shell pkg-config --cflags thrift)
 THRIFT_FLAGS += -I$(GEN_DIR)
+ifeq ($(OS),Darwin)
+# get Homebrew prefix
+HOMEBREW_PREFIX := $(shell brew --prefix)
+# get boost include path (no pkgconfig file)
+BOOST_INCLUDE := $(shell find $(HOMEBREW_PREFIX) -path '*/Cellar/boost/*/include' -type d | head -n 1)
+THRIFT_FLAGS += -I$(BOOST_INCLUDE)
+THRIFT_FLAGS += $(shell pkg-config --cflags openssl)
+endif
 THRIFT_LIBS = $(shell pkg-config --libs thrift)
 
 all: hello_client hello_client_compact hello_client_ssl hello_client_py.stamp
diff --git a/samples/modules/thrift/hello/server/Makefile b/samples/modules/thrift/hello/server/Makefile
index 20fc9bf625c3d..7f98ded3fef43 100644
--- a/samples/modules/thrift/hello/server/Makefile
+++ b/samples/modules/thrift/hello/server/Makefile
@@ -3,6 +3,8 @@
 
 .PHONY: all clean
 
+OS = $(shell uname -s)
+
 CXXFLAGS :=
 CXXFLAGS += -std=c++17
 
@@ -14,6 +16,14 @@ GENOBJ = $(filter-out %.h, $(GENSRC:.cpp=.o))
 THRIFT_FLAGS :=
 THRIFT_FLAGS += $(shell pkg-config --cflags thrift)
 THRIFT_FLAGS += -I$(GEN_DIR)
+ifeq ($(OS),Darwin)
+# get Homebrew prefix
+HOMEBREW_PREFIX := $(shell brew --prefix)
+# get boost include path (no pkgconfig file)
+BOOST_INCLUDE := $(shell find $(HOMEBREW_PREFIX) -path '*/Cellar/boost/*/include' -type d | head -n 1)
+THRIFT_FLAGS += -I$(BOOST_INCLUDE)
+THRIFT_FLAGS += $(shell pkg-config --cflags openssl)
+endif
 THRIFT_LIBS :=
 THRIFT_LIBS = $(shell pkg-config --libs thrift)